- A allele: This represents the traditional haemoglobin, also referred to as haemoglobin A (HbA). Individuals with the “A” allele usually have regular pink blood cells.
- C allele: This represents haemoglobin C (HbC), which is a variant type of haemoglobin. Haemoglobin C is much less environment friendly at carrying oxygen in comparison with haemoglobin A. Individuals who inherit the “C” allele from one guardian could have pink blood cells which are extra fragile or have a shorter lifespan than regular.
Genotype AC:
An individual with the AC genotype has one regular haemoglobin allele (A) and one haemoglobin C allele (C). Usually, individuals with the AC genotype don’t have vital well being issues and lead regular lives.
Nonetheless, in sure conditions, akin to extreme dehydration or low oxygen ranges, they may expertise gentle signs like slight anaemia.
It’s essential to notice that the AC genotype is totally different from the sickle cell trait (AS) or sickle cell illness (SS).
Individuals with the AC genotype don’t have sickle cell illness, but when they’ve kids with somebody who carries the S allele (e.g., AS or SS genotypes), there’s a chance that their little one may inherit a mixture of those alleles, which could lead to sickle cell trait or illness.
In abstract, genotype AC is usually thought-about a benign situation, but it surely carries significance within the context of household planning and genetic counselling.